Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876389 | 1.00 | KRAS (0.33) | KRASDPP4 | |
| SCHEMBL25445663 | 0.88 | — | — | |
| SCHEMBL24876304 | 0.85 | KRAS (0.35) | KRAS | |
| SCHEMBL24876392 | 0.85 | KRAS (0.35) | KRAS | |
| SCHEMBL25673246 | 0.85 | DPP4 (0.32) | KRASDPP4 | |
| SCHEMBL25066395 | 0.84 | KRAS (0.32) | KRASDPP4 | |
| SCHEMBL25066412 | 0.84 | KRAS (0.32) | KRASDPP4 | |
| SCHEMBL24543364 | 0.78 | KRAS (0.38) | KRASDPP4 | |
| SCHEMBL25504812 | 0.78 | CHRM2 (0.34) | — | |
| SCHEMBL30064865 | 0.75 | CA1 (0.33) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091746-A1 | COMBINATION THERAPY COMPRISING AN FGFR INHIBITOR AND A KRAS INHIBITOR | INCYTE CORPORATION (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283213-A1 | TRICYCLIC COMPOUNDS AS INHIBITORS OF KRAS | INCYTE CORPORATION (US) | 2023-01-12 | — | — | WO | disclosed |