Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876293 | 0.85 | KRAS (0.33) | DPP4KRAS | |
| SCHEMBL24876389 | 0.85 | KRAS (0.33) | DPP4KRAS | |
| SCHEMBL25066412 | 0.81 | KRAS (0.32) | DPP4KRAS | |
| SCHEMBL25066395 | 0.81 | KRAS (0.32) | DPP4KRAS | |
| SCHEMBL30064865 | 0.75 | CA1 (0.33) | KRAS | |
| SCHEMBL24543364 | 0.75 | KRAS (0.38) | DPP4KRAS | |
| SCHEMBL25673352 | 0.75 | TACR1 (0.32) | KRASTACR1 | |
| SCHEMBL25445663 | 0.73 | — | — | |
| SCHEMBL24854345 | 0.72 | KRAS (0.37) | DPP4KRAS | |
| SCHEMBL22967640 | 0.72 | KRAS (0.37) | DPP4KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091746-A1 | COMBINATION THERAPY COMPRISING AN FGFR INHIBITOR AND A KRAS INHIBITOR | INCYTE CORPORATION (US) | 2023-05-25 | — | — | WO | disclosed |