Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 6/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | ITGA1 | P56199 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | SGK1 | O00141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31680027 | 1.00 | LMNA (0.54) | LMNATHRBPKMBRD4ITGA1 | |
| SCHEMBL24876606 | 0.93 | LMNA (0.54) | LMNATHRBPKMBRD4ITGA1 | |
| SCHEMBL31679972 | 0.93 | LMNA (0.54) | LMNATHRBPKMBRD4ITGA1 | |
| SCHEMBL31679854 | 0.90 | LMNA (0.69) | LMNATHRBPKMBRD4MEN1 | |
| SCHEMBL24875999 | 0.90 | LMNA (0.69) | LMNATHRBPKMBRD4MEN1 | |
| SCHEMBL24876630 | 0.89 | LMNA (0.54) | LMNATHRBPKMBRD4FABP4 | |
| SCHEMBL31680063 | 0.89 | LMNA (0.54) | LMNATHRBPKMBRD4FABP4 | |
| SCHEMBL31680039 | 0.84 | LMNA (0.54) | LMNATHRBPKMBRD4FABP4 | |
| SCHEMBL31679821 | 0.84 | LMNA (0.51) | LMNATHRBPKMBRD4ITGA1 | |
| SCHEMBL24876306 | 0.83 | LMNA (0.52) | LMNATHRBPKMBRD4FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |