Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876 | 1.00 | MEN1 (0.65) | MEN1KMT2AMAPTALDH1A1TP53 | |
| SCHEMBL1207521 | 0.90 | MEN1 (0.56) | MEN1KMT2AMAPTALDH1A1TP53 | |
| SCHEMBL1207522 | 0.90 | MEN1 (0.56) | MEN1KMT2AMAPTALDH1A1TP53 | |
| SCHEMBL9167221 | 0.89 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1TP53 | |
| SCHEMBL9167224 | 0.89 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1TP53 | |
| SCHEMBL4427602 | 0.89 | TTR (0.69) | MEN1KMT2AMAPTALDH1A1TP53 | |
| SCHEMBL4427604 | 0.89 | TTR (0.69) | MEN1KMT2AMAPTALDH1A1TP53 | |
| SCHEMBL1269502 | 0.84 | TTR (0.63) | MEN1KMT2AMAPTALDH1A1TP53 | |
| SCHEMBL1269501 | 0.84 | TTR (0.63) | MEN1KMT2AMAPTALDH1A1TP53 | |
| SCHEMBL3752885 | 0.84 | CA12 (0.69) | TTRDPP4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864374-B | Preparation method of ether high-water-retention polycarboxylate superplasticizer | 科之杰新材料集团有限公司 | 2021-05-25 | — | — | CN | claimed |
| CN-108864375-A | A kind of preparation method being retained anti-chamotte mould polycarboxylate water-reducer | 科之杰新材料集团有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108864374-A | A kind of preparation method of the high water-retaining type polycarboxylate water-reducer of ethers | 科之杰新材料集团有限公司 | 2018-11-23 | — | — | CN | claimed |
| CN-107698528-A | A kind of preparation method of 3-triazole compounds | 湖南华腾制药有限公司 | 2018-02-16 | — | — | CN | claimed |
| CN-108864374-B | Preparation method of ether high-water-retention polycarboxylate superplasticizer | 科之杰新材料集团有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-108864375-B | Preparation method of water-retention and mud-resistance type polycarboxylate superplasticizer | 科之杰新材料集团有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-108864374-A | A kind of preparation method of the high water-retaining type polycarboxylate water-reducer of ethers | 科之杰新材料集团有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108864375-A | A kind of preparation method being retained anti-chamotte mould polycarboxylate water-reducer | 科之杰新材料集团有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-107698528-A | A kind of preparation method of 3-triazole compounds | 湖南华腾制药有限公司 | 2018-02-16 | — | — | CN | disclosed |
| WO-2011161537-A2 | 3,4-DIHYDROPYRROLO[1,2-A]PYRAZINE-2,8(1H)-DICARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-12-29 | — | — | WO | disclosed |
| US-20110039893-A1 | GSK-3BETA INHIBITOR | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2011-02-17 | — | — | US | disclosed |
| EP-1047425-A4 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2009-04-22 | — | — | EP | disclosed |
| US-6066648-A | USEFUL IN INHIBITING BONE RESORPTION, TREATING AND PREVENTING OSTEOPOROSIS, AND INHIBITING VASCULAR RESTENOSIS, DIABETIC RETINOPATHY, MACULAR DEGENERATION, ANGIOGENESIS, ATHEROSCLEROSIS, INFLAMMATION, VIRAL DISEASE, AND TUMOR GROWTH | MERCK & CO., INC. (US) | 2000-05-23 | — | — | US | disclosed |
| US-6017926-A | Integrin receptor antagonists | MERCK & CO., INC. (US) | 2000-01-25 | — | — | US | disclosed |
| US-5981546-A | Integrin antagonists | MERCK & CO., INC. (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0934305-A1 | INTEGRIN ANTAGONISTS | Merck & Co., Inc. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1999031099-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999030709-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999030713-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| WO-1998008840-A1 | INTEGRIN ANTAGONISTS | MERCK & CO., INC. (US) | 1998-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039893-A1 | GSK-3BETA INHIBITOR | GSK3B, GSK3A, GSKIP | MEN1 1917/4885KMT2A 575/4885MAPT 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.