Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.69 |
| ▸ | CA7 | P43166 | 3/20 | 0.69 |
| ▸ | CA9 | Q16790 | 3/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.69 |
| ▸ | TTR | P02766 | 1/20 | 0.68 |
| ▸ | DPP4 | P27487 | 1/20 | 0.68 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | FDPS | P14324 | 1/20 | 0.55 |
| ▸ | MMP1 | P03956 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2389918 | 1.00 | CA12 (0.69) | CA12CA7CA9CA14CA1 | |
| SCHEMBL4427602 | 0.92 | TTR (0.69) | CA12CA7CA9CA14CA1 | |
| SCHEMBL4427604 | 0.92 | TTR (0.69) | CA12CA7CA9CA14CA1 | |
| SCHEMBL1269501 | 0.87 | TTR (0.63) | CA12CA7CA9CA14CA1 | |
| SCHEMBL1269502 | 0.87 | TTR (0.63) | CA12CA7CA9CA14CA1 | |
| SCHEMBL27934208 | 0.86 | TTR (0.61) | CA12CA7CA9CA14CA1 | |
| SCHEMBL27792939 | 0.86 | KDM4E (0.64) | CA12CA7CA9CA14CA1 | |
| SCHEMBL1578506 | 0.86 | KDM4E (0.64) | CA12CA7CA9CA14CA1 | |
| SCHEMBL1578505 | 0.86 | KDM4E (0.64) | CA12CA7CA9CA14CA1 | |
| SCHEMBL1579811 | 0.86 | TTR (0.61) | CA12CA7CA9CA14CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905249-A | A kind of preparation method of azepine class compound | 长沙深橙生物科技有限公司 | 2017-06-30 | — | — | CN | claimed |
| CN-106905249-A | A kind of preparation method of azepine class compound | 长沙深橙生物科技有限公司 | 2017-06-30 | — | — | CN | disclosed |
| CN-1829442-B | Safeners based on aromatic-aliphatic carboxylic acid derivatives | BAYER CROPSCIENCE GMBH | 2011-05-04 | — | — | CN | disclosed |
| CN-102028690-A | Application of ligustrazine cinnamic acid phenolic ether derivatives in preparing medicines | UNIV SHANDONG | 2011-04-27 | — | — | CN | disclosed |
| US-7838463-B2 | Safeners based on acrylic-aliphatic carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-11-23 | — | — | US | disclosed |
| EP-1040103-B1 | ANILIDE DERIVATIVE, PRODUCTION AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2007-03-14 | — | — | EP | disclosed |
| CN-1829442-A | Safeners based on aromatic-aliphatic carboxylic acid derivatives | BAYER CROPSCIENCE GMBH (DE) | 2006-09-06 | — | — | CN | disclosed |
| US-20050049145-A1 | Safeners based on acrylic-aliphatic carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2005-03-03 | — | — | US | disclosed |
| US-6413947-B1 | Anilide derivative, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| US-6268354-B1 | Pharmaceutical composition for antagonizing CCR5 comprising anilide derivative | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-07-31 | — | — | US | disclosed |
| WO-1994001414-A1 | URACIL DERIVATIVES AS ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-01-20 | — | — | WO | disclosed |
| US-5137889-A | Hypotensive agents; coronary vasodilators; calcium antagonists; antiinflammatory agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-5034395-A | Hypotensive agents, carboxylated dihydropyridines | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| US-4845016-A | SHORT DEVELOPMENT TIME, FREE OF BENZYL ALCOHOL | FUJI PHOTO FILM CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4795814-A | CORONARY VASODILATORS, HYPOTENSIVE AGENTS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTTS, ENZYME INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-01-03 | — | — | US | disclosed |
| EP-0173126-A1 | Process for preparing novel dihydropyridine derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| US-4456682-A | PHOTOSENSITIVITY, PYRAZOLIDONE COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1984-06-26 | — | — | US | disclosed |
| US-4409324-A | HIGH BOILING SOLVENT, OIL SOLUBLE PYRAZOLIDONE COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1983-10-11 | — | — | US | disclosed |
| US-4383027-A | 1-PHENYL-3-ANILINO-4-PHENYLTHIO-5-PYRAZOLONE, 1-PHENYL-3-PYRAZOLIDONE | FUJI PHOTO FILM CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050049145-A1 | Safeners based on acrylic-aliphatic carboxylic acid derivatives | GRHPR, HCAR1, HCAR3 | CA12 2611/4885CA7 1335/4885CA9 2176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.