Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11121512 | 0.82 | SLC18A3 (1.00) | SLC18A3CYP2D6CYP2C19GRIN2BSMN1; SMN2 | |
| SCHEMBL7888827 | 0.82 | SLC18A3 (1.00) | SLC18A3CYP2D6CYP2C19GRIN2BSMN1; SMN2 | |
| SCHEMBL299929 | 0.82 | CYP2D6 (0.68) | SLC18A3CYP2D6CYP2C19GRIN2BSMN1; SMN2 | |
| SCHEMBL14720645 | 0.81 | SLC18A3 (0.83) | SLC18A3CYP2D6CYP2C19GRIN2BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7879553 | 0.81 | SLC18A3 (0.96) | SLC18A3CYP2D6CYP2C19GRIN2BSMN1; SMN2 | |
| SCHEMBL24869954 | 0.81 | SLC18A3 (0.47) | SLC18A3CYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL30563652 | 0.80 | SLC18A3 (0.96) | SLC18A3CYP2D6CYP2C19GRIN2BSMN1; SMN2 | |
| SCHEMBL27894548 | 0.79 | CYP2D6 (0.65) | SLC18A3CYP2D6CYP2C19SMN1; SMN2HPGD | |
| SCHEMBL24163290 | 0.78 | SLC18A3 (0.79) | SLC18A3CYP2D6CYP2C19GRIN2BSMN1; SMN2 | |
| SCHEMBL13660519 | 0.78 | SLC18A3 (0.57) | SLC18A3CYP2D6CYP2C19SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283425-A1 | ARYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT MODULATE IKZF2 | Plexium, Inc. (US) | 2023-01-12 | — | — | WO | disclosed |