⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119173 | 0.71 | — | — | |
| SCHEMBL730744 | 0.71 | — | — | |
| SCHEMBL1270177 | 0.69 | — | — | |
| SCHEMBL731502 | 0.67 | — | — | |
| SCHEMBL5736389 | 0.67 | — | — | |
| SCHEMBL9025056 | 0.67 | — | — | |
| SCHEMBL5647294 | 0.66 | — | — | |
| SCHEMBL10653343 | 0.65 | — | — | |
| SCHEMBL3023260 | 0.64 | ALDH1A1 (0.40) | — | |
| SCHEMBL1246069 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | claimed |
| CN-100491358-C | Pyrimidinone compounds, compositions and methods | CYTOKINETICS INC SMITHKLINE BE (US) | 2009-05-27 | — | — | CN | claimed |
| US-7524594-B2 | Photosensitive dielectric resin compositions, films formed therefrom and semiconductor and display devices encompassing such films | PROMERUS LLC (US) | 2009-04-28 | — | — | US | claimed |
| EP-1713465-A4 | COMPOUNDS AND COMPOSITIONS AS LXR MODULATORS | IRM LLC (BM) | 2009-04-22 | — | — | EP | claimed |
| EP-1778759-B1 | PHOTOSENSITIVE DIELECTRIC RESIN COMPOSITIONS AND THEIR USES | PROMERUS LLC (US) | 2008-11-12 | — | — | EP | claimed |
| US-20070293547-A1 | Compounds and Compositions as Lxr Modulators | IRM LLC (BM) | 2007-12-20 | — | — | US | claimed |
| EP-1778759-A1 | PHOTOSENSITIVE DIELECTRIC RESIN COMPOSITIONS AND THEIR USES | Promerus, LLC (US) | 2007-05-02 | — | — | EP | claimed |
| EP-1713465-A2 | COMPOUNDS AND COMPOSITIONS AS LXR MODULATORS | IRM LLC (BM) | 2006-10-25 | — | — | EP | claimed |
| EP-1682534-A2 | PYRIMIDIN-4-ONE COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-07-26 | — | — | EP | claimed |
| WO-2006017035-A1 | PHOTOSENSITIVE DIELECTRIC RESIN COMPOSITIONS AND THEIR USES | PROMERUS LLC (US) | 2006-02-16 | — | — | WO | claimed |
| US-20050197327-A1 | Compounds, compositions, and methods | CYTOKINETICS, INCORPORATED | 2005-09-08 | — | — | US | claimed |
| CN-1665788-A | Pyrimidinone compounds, compositions and methods | CYTOKINETICS INC (US) | 2005-09-07 | — | — | CN | claimed |
| WO-2005077122-A2 | COMPOUNDS AND COMPOSITIONS AS LXR MODULATORS | IRM LLC (BM) | 2005-08-25 | — | — | WO | claimed |
| WO-2005041888-A2 | PYRIMIDIN-4-ONE COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2005-05-12 | — | — | WO | claimed |
| EP-1511383-A1 | SUBSTITUTED PHENYLURACILS | Bayer CropScience Aktiengesellschaft (DE) | 2005-03-09 | — | — | EP | claimed |
| WO-2003099009-A1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-12-04 | — | — | WO | claimed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | claimed |
| US-5543406-A | TREATING ANDROGEN RESPONSIVE OR MEDIATED DISEASE | GLAXO WELLCOME, INC. (US) | 1996-08-06 | — | — | US | claimed |
| EP-0641356-A1 | INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE | GLAXO WELLCOME INC. (US) | 1995-03-08 | — | — | EP | claimed |
| WO-1993013124-A1 | INHIBITORS OF 5-ALPHA-TESTOSTERONE REDUCTASE | GLAXO INC. (US) | 1993-07-08 | — | — | WO | claimed |