Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.79 |
| ▸ | HTT | P42858 | 1/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.72 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | MB | P02144 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615418 | 0.94 | KMT2A (0.81) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL1753885 | 0.94 | KMT2A (0.81) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL30443411 | 0.91 | KMT2A (0.78) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL3818831 | 0.89 | SMN1; SMN2 (1.00) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL31500695 | 0.88 | KMT2A (0.66) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL4455279 | 0.88 | KMT2A (0.72) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL9762638 | 0.83 | SMN1; SMN2 (0.86) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL10924278 | 0.82 | KMT2A (0.68) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL14384682 | 0.82 | KMT2A (0.66) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 | |
| SCHEMBL17316953 | 0.82 | HTT (0.63) | SMN1; SMN2HTTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280294-A1 | TARGET AND SMALL MOLECULE COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES OR CENTRAL NERVOUS SYSTEM INJURY | 北京干细胞与再生医学研究院 | 2023-01-12 | — | — | WO | disclosed |