Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516221 | 0.90 | KMT2A (0.73) | KMT2AMEN1POLBMTNR1AMTNR1B | |
| SCHEMBL1753885 | 0.88 | KMT2A (0.81) | KMT2AMEN1POLBLMNATDP1 | |
| SCHEMBL2615418 | 0.88 | KMT2A (0.81) | KMT2AMEN1POLBLMNATDP1 | |
| Hydrochloric Acid SCHEMBL30443411 | 0.86 | KMT2A (0.78) | KMT2AMEN1POLBLMNATDP1 | |
| SCHEMBL14384856 | 0.85 | MTNR1A (0.64) | KMT2APOLBMTNR1AMTNR1BLMNA | |
| SCHEMBL18826484 | 0.85 | KMT2A (0.66) | KMT2AMEN1POLBMTNR1AMTNR1B | |
| SCHEMBL14384396 | 0.83 | MTNR1A (0.76) | KMT2AMEN1POLBMTNR1AMTNR1B | |
| SCHEMBL2844063 | 0.83 | KMT2A (0.77) | KMT2AMEN1POLBMTNR1AMTNR1B | |
| SCHEMBL171438 | 0.83 | HPGD (0.71) | KMT2AMEN1POLBMTNR1AMTNR1B | |
| SCHEMBL14192610 | 0.83 | KMT2A (0.63) | KMT2AMEN1POLBMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007130743-A2 | CAPREOMYCIN DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | ARRAY BIOPHARMA, INC. (US) | 2007-11-15 | — | — | WO | disclosed |