SCHEMBL24878804

SCHEMBL24878804

CC(=O)Nc1ccn(C2CC(OC(C)=O)C(COP=O)O2)c(=O)n1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.54
ABL1 P00519 1/20 0.39
RIN1 Q13671 1/20 0.39
NT5E P21589 2/20 0.37
MAPT P10636 1/20 0.36
P2RY6 Q15077 6/20 0.35
P2RY2 P41231 5/20 0.35
P2RY4 P51582 5/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ROCK2 O75116 1/20 0.35
P2RY14 Q15391 2/20 0.35
P2RY1 P47900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9756890 0.88 POLB (0.67) POLBABL1RIN1NT5EMAPT
SCHEMBL14429264 0.83 POLB (0.58) POLBABL1RIN1NT5EMAPT
SCHEMBL14429272 0.83 POLB (0.58) POLBABL1RIN1NT5EMAPT
SCHEMBL26803701 0.82 POLB (0.46) POLBABL1RIN1NT5EMAPT
SCHEMBL2582769 0.82 POLB (0.52) POLBABL1RIN1NT5EP2RY6
SCHEMBL9602217 0.80 POLB (0.72) POLBABL1RIN1NT5EP2RY6
SCHEMBL14429265 0.80 POLB (0.47) POLBABL1RIN1NT5EP2RY2
SCHEMBL14440228 0.80 POLB (0.47) POLBABL1RIN1NT5EP2RY2
SCHEMBL14568442 0.80 POLB (0.47) POLBABL1RIN1NT5EP2RY2
SCHEMBL14429259 0.80 POLB (0.47) POLBABL1RIN1NT5EP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023281514-A1 NUCLEIC ACID MOLECULE AND ITS USE RNA MORPH LTD (IL) 2023-01-12 WO disclosed