Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 4/20 | 0.33 |
| ▸ | GSK3B | P49841 | 4/20 | 0.33 |
| ▸ | CDK1 | P06493 | 3/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27453727 | 0.90 | PTPN11 (0.33) | GSK3AGSK3BCDK1CCNB1CCNB2 | |
| SCHEMBL30987309 | 0.82 | GSK3A (0.40) | GSK3AGSK3BCDK1CCNB1CCNB2 | |
| SCHEMBL31723354 | 0.76 | PTPN11 (0.33) | — | |
| SCHEMBL24878893 | 0.75 | BRAF (0.39) | TNFBRAF | |
| SCHEMBL27453722 | 0.74 | GSK3A (0.36) | GSK3AGSK3BCDK1CCNB1CCNB2 | |
| SCHEMBL31723372 | 0.73 | PTPN11 (0.34) | TNF | |
| SCHEMBL30987346 | 0.70 | PTPN11 (0.60) | — | |
| SCHEMBL27240711 | 0.70 | PTPN11 (0.62) | — | |
| SCHEMBL30111077 | 0.70 | PTPN11 (0.62) | — | |
| SCHEMBL27453182 | 0.70 | PTPN11 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023282702-A1 | SHP2 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-01-12 | — | — | WO | disclosed |