Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 19/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24878893 | 0.85 | BRAF (0.39) | PTPN11KCNH2TNF | |
| SCHEMBL27453727 | 0.84 | PTPN11 (0.33) | PTPN11KCNH2 | |
| SCHEMBL31723368 | 0.79 | PTPN11 (0.60) | PTPN11 | |
| SCHEMBL30987321 | 0.77 | PTPN11 (0.60) | PTPN11KCNH2 | |
| SCHEMBL30987318 | 0.77 | PTPN11 (0.60) | PTPN11KCNH2 | |
| SCHEMBL31723355 | 0.74 | BRAF (0.36) | TNF | |
| SCHEMBL31723357 | 0.74 | TNF (0.36) | TNF | |
| SCHEMBL24879129 | 0.73 | GSK3A (0.33) | TNF | |
| SCHEMBL31723354 | 0.72 | PTPN11 (0.33) | PTPN11KCNH2 | |
| SCHEMBL24879223 | 0.70 | PARP1 (0.40) | PTPN11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4647433-A1 | SHP2 INHIBITOR AND USES THEREOF | Kanaph Therapeutics Inc. (KR) | 2025-11-12 | — | — | EP | disclosed |