Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | NQO2 | P16083 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29131166 | 0.81 | HSD17B10 (0.52) | HSD17B10NAPRTNQO2ALDH1A1KMT2A | |
| SCHEMBL7188387 | 0.79 | MAPT (0.57) | HSD17B10NAPRTNQO2ALDH1A1KMT2A | |
| SCHEMBL29131182 | 0.79 | HSD17B10 (0.57) | HSD17B10NAPRTNQO2ALDH1A1KMT2A | |
| SCHEMBL5433837 | 0.78 | HSD17B10 (0.62) | HSD17B10NQO2ALDH1A1KMT2AMEN1 | |
| SCHEMBL11622379 | 0.77 | KMT2A (0.57) | HSD17B10NAPRTNQO2ALDH1A1KMT2A | |
| Biphenyl SCHEMBL9009636 | 0.77 | NAPRT (0.86) | HSD17B10NAPRTNQO2ALDH1A1KMT2A | |
| SCHEMBL29320926 | 0.77 | NPSR1 (0.43) | HSD17B10ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3030037 | 0.76 | LMNA (0.60) | HSD17B10NAPRTALDH1A1KMT2AMEN1 | |
| SCHEMBL29131177 | 0.76 | KMT2A (0.57) | HSD17B10NAPRTNQO2ALDH1A1KMT2A | |
| Acetanilide SCHEMBL6693944 | 0.76 | HSD17B10 (0.76) | HSD17B10NAPRTNQO2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280294-A1 | TARGET AND SMALL MOLECULE COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES OR CENTRAL NERVOUS SYSTEM INJURY | 北京干细胞与再生医学研究院 | 2023-01-12 | — | — | WO | disclosed |