Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 8/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.55 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.55 |
| ▸ | STAT6 | P42226 | 12/20 | 0.55 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2386825 | 0.99 | SYK (0.59) | SYKKCNH2AURKBZAP70STAT6 | |
| SCHEMBL737980 | 0.86 | SYK (0.62) | SYKKCNH2AURKBZAP70STAT6 | |
| SCHEMBL763619 | 0.84 | SYK (0.62) | SYKKCNH2AURKBZAP70STAT6 | |
| SCHEMBL4713716 | 0.81 | SYK (0.66) | SYKKCNH2AURKBZAP70STAT6 | |
| SCHEMBL2388956 | 0.81 | SYK (0.66) | SYKKCNH2AURKBZAP70STAT6 | |
| SCHEMBL2388556 | 0.81 | SYK (0.64) | SYKKCNH2AURKBZAP70STAT6 | |
| SCHEMBL2493850 | 0.80 | SYK (0.72) | SYKKCNH2AURKBZAP70STAT6 | |
| SCHEMBL2385345 | 0.80 | SYK (0.64) | SYKKCNH2AURKBZAP70STAT6 | |
| Hydrochloric Acid SCHEMBL2385618 | 0.79 | SYK (0.71) | SYKKCNH2AURKBZAP70STAT6 | |
| SCHEMBL737705 | 0.79 | SYK (0.64) | SYKKCNH2AURKBZAP70STAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1518855-B1 | DIAMINOPYRIMIDINECARBOXA MIDE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2011-10-26 | — | — | EP | disclosed |