Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14300347 | 1.00 | GSK3B (0.51) | GSK3BCYP2D6 | |
| SCHEMBL13046421 | 0.89 | GSK3B (0.48) | GSK3BCYP2D6 | |
| SCHEMBL2488560 | 0.88 | GSK3B (0.53) | GSK3BCYP2D6 | |
| SCHEMBL2488485 | 0.88 | GSK3B (0.53) | GSK3BCYP2D6 | |
| SCHEMBL3752234 | 0.88 | GSK3B (0.53) | GSK3BCYP2D6 | |
| SCHEMBL2488521 | 0.84 | GSK3B (0.61) | GSK3BCYP2D6 | |
| SCHEMBL14300349 | 0.84 | GSK3B (0.61) | GSK3BCYP2D6 | |
| SCHEMBL12207407 | 0.84 | GSK3B (0.51) | GSK3BCYP2D6 | |
| SCHEMBL2490220 | 0.84 | GSK3B (0.51) | GSK3BCYP2D6 | |
| SCHEMBL13046794 | 0.82 | GSK3B (0.47) | GSK3BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057141-B1 | PYRIMIDONE COMPOUNDS AS GSK-3 INHIBITORS | PFIZER PROD INC (US) | 2011-10-26 | — | — | EP | disclosed |
| US-20100292205-A1 | Pyrimidone Compounds As GSK-3 Inhibitors | PFIZER INC. (US) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292205-A1 | Pyrimidone Compounds As GSK-3 Inhibitors | GSK3B, GSK3A, GSKIP | GSK3B 1/4885CYP2D6 516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.