Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HCAR1 | Q9BXC0 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27695976 | 0.81 | PI4KA (0.55) | HCAR1CYP3A4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL30677290 | 0.79 | CYP1A2 (0.46) | CYP3A4CYP2C19CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL6944930 | 0.78 | PI4KA (0.55) | POLBHCAR1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL29240138 | 0.75 | PI4KA (0.57) | POLBHCAR1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL28950114 | 0.74 | SRC (0.44) | HCAR1CYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL30025787 | 0.74 | POLB (0.64) | POLBHCAR1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL680855 | 0.73 | FGFR1 (0.56) | HCAR1CYP3A4CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL2194556 | 0.73 | HCAR1 (0.54) | POLBHCAR1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL28204981 | 0.73 | POLB (0.43) | POLBCYP3A4CYP2C19CYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4456679 | 0.72 | FGFR1 (0.54) | HCAR1CYP3A4CYP2C19CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379555-A1 | PURINE COMPOUNDS | Eli Lilly and Company (US) | 2011-10-26 | — | — | EP | claimed |
| WO-2010080306-A1 | PURINE COMPOUNDS | ELI LILLY AND COMPANY (US) | 2010-07-15 | — | — | WO | claimed |