Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.53 |
| ▸ | PPARA | Q07869 | 5/20 | 0.53 |
| ▸ | PPARD | Q03181 | 2/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31140048 | 1.00 | PPARG (0.53) | PPARGPPARAPPARDAKR1C3PANK3 | |
| SCHEMBL31274469 | 0.84 | PPARG (0.48) | PPARGPPARAPPARDAKR1C3PANK3 | |
| SCHEMBL31108113 | 0.84 | GPR119 (0.43) | PANK3GPR119SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL31464918 | 0.82 | PANK3 (0.54) | PANK3 | |
| SCHEMBL30860022 | 0.82 | PANK3 (0.54) | PANK3 | |
| SCHEMBL594352 | 0.81 | AKR1C3 (0.57) | PPARGPPARAPPARDAKR1C3PANK3 | |
| SCHEMBL30480343 | 0.81 | AKR1C3 (0.57) | PPARGPPARAPPARDAKR1C3PANK3 | |
| SCHEMBL13100992 | 0.81 | AKR1C3 (0.51) | PPARGPPARAPPARDAKR1C3PANK3 | |
| SCHEMBL29990449 | 0.81 | PPARG (0.45) | PPARGPPARAPPARDAKR1C3PANK3 | |
| SCHEMBL24670864 | 0.81 | PPARG (0.45) | PPARGPPARAPPARDAKR1C3PANK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118440054-A | Degradation agent, composition and application of cyclin-dependent kinase 12/13 | 浙江大学 | 2024-08-06 | — | — | CN | disclosed |
| CN-117940414-A | Compounds for targeting IRAK4 protein degradation | 渤健马萨诸塞州股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| WO-2023283610-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS | BIOGEN MA INC. (US) | 2023-01-12 | — | — | WO | disclosed |
| CN-1083475-A | Acetogenin | GLAXO GROUP LTD (GB) | 1994-03-09 | — | — | CN | disclosed |