Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21227516 | 1.00 | TYK2 (0.45) | TYK2 | |
| SCHEMBL20687689 | 0.83 | IRAK4 (0.39) | TYK2 | |
| SCHEMBL20687676 | 0.83 | IRAK4 (0.39) | TYK2 | |
| SCHEMBL23583155 | 0.83 | IRAK4 (0.39) | TYK2 | |
| SCHEMBL20688147 | 0.83 | TYK2 (0.52) | TYK2 | |
| SCHEMBL21227384 | 0.83 | TYK2 (0.52) | TYK2 | |
| SCHEMBL21227385 | 0.83 | TYK2 (0.52) | TYK2 | |
| SCHEMBL20688144 | 0.83 | TYK2 (0.52) | TYK2 | |
| SCHEMBL25295602 | 0.80 | TYK2 (0.41) | TYK2 | |
| SCHEMBL20688188 | 0.80 | TYK2 (0.48) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283610-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS | BIOGEN MA INC. (US) | 2023-01-12 | — | — | WO | disclosed |