Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158596 | 0.91 | ACLY (0.53) | ACLYNPSR1KDM4ERXFP1MCL1 | |
| SCHEMBL2158009 | 0.88 | ACLY (0.53) | ACLYNPSR1KDM4ERXFP1MCL1 | |
| SCHEMBL6426603 | 0.87 | NPSR1 (0.60) | ACLYNPSR1KDM4ERXFP1 | |
| SCHEMBL2157930 | 0.87 | ACLY (0.55) | ACLYNPSR1KDM4ERXFP1 | |
| SCHEMBL2158668 | 0.86 | ACLY (0.67) | ACLYNPSR1KDM4ERXFP1 | |
| SCHEMBL12371087 | 0.86 | ACLY (0.50) | ACLYNPSR1KDM4ERXFP1MCL1 | |
| SCHEMBL2157623 | 0.86 | ACLY (0.49) | ACLYNPSR1KDM4ERXFP1MCL1 | |
| SCHEMBL2158516 | 0.85 | NPSR1 (0.52) | ACLYNPSR1KDM4ERXFP1 | |
| SCHEMBL6426920 | 0.84 | NPSR1 (0.56) | ACLYNPSR1KDM4ERXFP1 | |
| SCHEMBL2158232 | 0.84 | NPSR1 (0.61) | ACLYNPSR1KDM4ERXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2363396-A1 | Thiophene derivatives as antiviral agents for flavivirus infection | Virochem Pharma Inc. (CA) | 2011-09-07 | — | — | EP | disclosed |