Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxyphenonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.98 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.98 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.98 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.98 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxyphenonium SCHEMBL250615 | 0.99 | CHRM2 (1.00) | CHRM2CHRM1KCNH2SLC6A3LMNA | |
| Oxyphenonium SCHEMBL250614 | 0.99 | CHRM2 (1.00) | CHRM2CHRM1KCNH2SLC6A3LMNA | |
| Oxyphenonium SCHEMBL2030870 | 0.98 | CHRM2 (0.98) | CHRM2CHRM1KCNH2SLC6A3LMNA | |
| SCHEMBL23489737 | 0.90 | CHRM2 (0.84) | CHRM2CHRM1KCNH2SLC6A3LMNA | |
| SCHEMBL2999990 | 0.88 | CHRM2 (0.81) | CHRM2CHRM1KCNH2SLC6A3LMNA | |
| Hydrochloric Acid SCHEMBL29894890 | 0.88 | CHRM2 (0.81) | CHRM2CHRM1KCNH2SLC6A3LMNA | |
| SCHEMBL13266147 | 0.84 | POLB (0.76) | CHRM2CHRM1KCNH2SLC6A3LMNA | |
| SCHEMBL16887879 | 0.82 | CHRM2 (0.71) | CHRM2CHRM1KCNH2SLC6A3LMNA | |
| SCHEMBL290176 | 0.81 | CHRM2 (0.70) | CHRM2CHRM1KCNH2SLC6A3LMNA | |
| SCHEMBL13574067 | 0.81 | CHRM2 (0.70) | CHRM2CHRM1KCNH2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4467974-A1 | NOVEL CHEMOSENSORS AND THEIR USE IN ELECTROCHEMICAL DETECTION METHODS | Karlsruher Institut für Technologie (DE) | 2024-11-27 | — | — | EP | claimed |
| EP-4419619-A1 | SELECTIVE WET ETCH COMPOSITION AND METHOD | Entegris, Inc. (US) | 2024-08-28 | — | — | EP | claimed |
| US-11978622-B2 | Aqueous and semi-aqueous cleaners for the removal of post-etch residues with tungsten and cobalt compatibility | ENTEGRIS, INC. (US) | 2024-05-07 | — | — | US | claimed |
| WO-2023069409-A1 | SELECTIVE WET ETCH COMPOSITION AND METHOD | ENTEGRIS, INC. (US) | 2023-04-27 | — | — | WO | claimed |
| US-20230121639-A1 | SELECTIVE WET ETCH COMPOSITION AND METHOD | ENTEGRIS, INC. | 2023-04-20 | — | — | US | claimed |
| CN-115605297-A | Plasma coating treatment method for inhibiting transfer of biological pathogens | 分子等离子集团股份有限公司（LU） | 2023-01-13 | — | — | CN | claimed |
| CN-114401633-A | Pest control method, pest control agent composition, and pest control agent set | 日本曹达株式会社 | 2022-04-26 | — | — | CN | claimed |
| US-11124746-B2 | Post CMP cleaning composition | ENTEGRIS, INC. (US) | 2021-09-21 | — | — | US | claimed |
| EP-2964725-B1 | COMPOSITIONS AND METHODS FOR SELECTIVELY ETCHING TITANIUM NITRIDE | ENTEGRIS INC (US) | 2021-06-23 | — | — | EP | claimed |
| CN-110239944-B | Ring main unit cabinet combining and inserting device and method | 常州博瑞电力自动化设备有限公司 | 2021-05-11 | — | — | CN | claimed |
| EP-2026807-A1 | USE OF PARASYMPATHOLYTIC SUBSTANCES TO ENHANCE AND ACCELERATE STEM CELL DIFFERENTIATION, RELATED METHOD AND COMPOSITIONS | Universita' Degli Studi di Torino (IT) | 2009-02-25 | — | — | EP | claimed |
| WO-2007135574-A1 | USE OF PARASYMPATHOLYTIC SUBSTANCES TO ENHANCE AND ACCELERATE STEM CELL DIFFERENTIATION, RELATED METHOD AND COMPOSITIONS | UNIVERSITA' DEGLI STUDI DI TORINO (IT) | 2007-11-29 | — | — | WO | claimed |
| EP-1273301-B1 | Pharmaceutical preparations based on active ingredients susceptible to illicit administration | ALTERGON SA (CH) | 2006-09-06 | — | — | EP | claimed |
| EP-1273301-A2 | Pharmaceutical preparations based on active ingredients susceptible to illicit administration | ALTERGON S.A. (CH) | 2003-01-08 | — | — | EP | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| EP-1072260-A1 | Transdermal systems for the release of muscarinic receptor antagonists and use thereof for treatement of smooth muscle spasms in urology | Novosis Pharma AG (DE) | 2001-01-31 | — | — | EP | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| US-5008111-A | Pretreating skin with anticholinergic quaternary ammonium salt to suppress perspiration | SCHERING CORPORATION (US) | 1991-04-16 | — | — | US | claimed |
| US-4824676-A | ANTICHOLINERGIC AGENT TO SUPPRESS PERSPIRATION | SCHERING CORPORATION (US) | 1989-04-25 | — | — | US | claimed |
| EP-0140434-A2 | Pharmaceutical composition with systemic anticholineesterasic, agonistic-cholinergic and antimuscarinic activity | PRODOTTI FORMENTI S.r.l. (IT) | 1985-05-08 | — | — | EP | claimed |