SCHEMBL290176

SCHEMBL290176

CCOC(=O)C(O)(c1ccccc1)C1CCCCC1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 4/20 0.70
CHRM1 P11229 3/20 0.70
KCNH2 Q12809 3/20 0.70
SLC6A3 Q01959 2/20 0.70
POLB P06746 1/20 0.69
ALDH1A1 P00352 2/20 0.68
CYP2C19 P33261 2/20 0.67
CYP3A4 P08684 2/20 0.67
CHRM3 P20309 2/20 0.67
CYP1A2 P05177 1/20 0.67
CYP2D6 P10635 1/20 0.67
CYP2C9 P11712 1/20 0.67
PKM P14618 1/20 0.67
NFKB1 P19838 1/20 0.67
THPO P40225 1/20 0.67
ABCB11 O95342 1/20 0.67
ESR1 P03372 1/20 0.67
CHRM4 P08173 1/20 0.67
CHRM5 P08912 1/20 0.67
ADRA2A P08913 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13574067 1.00 CHRM2 (0.70) CHRM2CHRM1KCNH2SLC6A3POLB
SCHEMBL13574070 1.00 CHRM2 (0.70) CHRM2CHRM1KCNH2SLC6A3POLB
SCHEMBL5667254 0.99 ALDH1A1 (0.70) CHRM2CHRM1KCNH2SLC6A3POLB
SCHEMBL3913293 0.99 ALDH1A1 (0.70) CHRM2CHRM1KCNH2SLC6A3POLB
SCHEMBL13266147 0.88 POLB (0.76) CHRM2CHRM1KCNH2SLC6A3POLB
SCHEMBL4200385 0.87 ALDH1A1 (0.55) CHRM2CHRM1KCNH2SLC6A3POLB
SCHEMBL13241387 0.86 CHRM2 (0.78) CHRM2CHRM1KCNH2SLC6A3POLB
SCHEMBL13241377 0.85 CHRM2 (0.77) CHRM2CHRM1KCNH2SLC6A3POLB
SCHEMBL2760340 0.85 CHRM2 (0.73) CHRM2CHRM1KCNH2SLC6A3POLB
SCHEMBL1610849 0.85 KEAP1 (0.68) CHRM2CHRM1KCNH2SLC6A3POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10449173-B2 Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions ALLERGAN SALES, LLC (US) 2019-10-22 US claimed
EP-3287122-B1 DEVICE FOR STORAGE AND ADMINISTRATION OF TOPICAL OXYBUTYNIN COMPOSITIONS FOR TREATING OVERACTIVE BLADDERS. ALLERGAN SALES LLC (US) 2019-04-17 EP claimed
EP-3287122-A1 A METHOD FOR TREATING OVERACTIVE BLADDERS AND A DEVICE FOR STORAGE AND ADMINISTRATION OF TOPICAL OXYBUTYNIN COMPOSITIONS Allergan Sales, LLC (US) 2018-02-28 EP claimed
EP-2427172-B1 A METHOD FOR TREATING OVERACTIVE BLADDERS AND A DEVICE FOR STORAGE AND ADMINISTRATION OF TOPICAL OXYBUTYNIN COMPOSITIONS ALLERGAN SALES LLC (US) 2017-11-01 EP claimed
US-20160128963-A1 METHOD FOR TREATING OVERACTIVE BLADDERS AND A DEVICE FOR STORAGE AND ADMINISTRATION OF TOPICAL OXYBUTYNIN COMPOSITIONS WATSON LABORATORIES, INC. 2016-05-12 US claimed
US-9259388-B2 Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions WATSON PHARMACEUTICALS, INC. (US) 2016-02-16 US claimed
US-8920392-B2 Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions WATSON LABORATORIES, INC. (US) 2014-12-30 US claimed
US-20140046275-A1 Method for Treating Overactive Bladders and a Device for Storage and Administration of Topical Oxybutynin Compositions WATSON LABORATORIES, INC. (US) 2014-02-13 US claimed
EP-2427172-A2 A METHOD FOR TREATING OVERACTIVE BLADDERS AND A DEVICE FOR STORAGE AND ADMINISTRATION OF TOPICAL OXYBUTYNIN COMPOSITIONS Watson Laboratories, Inc. (US) 2012-03-14 EP claimed
WO-2010129498-A2 A METHOD FOR TREATING OVERACTIVE BLADDERS AND A DEVICE FOR STORAGE AND ADMINISTRATION OF TOPICAL OXYBUTYNIN COMPOSITIONS WATSON LABORATORIES, INC. (US) 2010-11-11 WO claimed
US-20100286630-A1 Method For Treating Overactive Bladders And A Device For Storage And Administration Of Topical Oxybutynin Compositions WATSON LABORATORIES, INC. (US) 2010-11-11 US claimed
US-10449173-B2 Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions ALLERGAN SALES, LLC (US) 2019-10-22 US disclosed
EP-3287122-B1 DEVICE FOR STORAGE AND ADMINISTRATION OF TOPICAL OXYBUTYNIN COMPOSITIONS FOR TREATING OVERACTIVE BLADDERS. ALLERGAN SALES LLC (US) 2019-04-17 EP disclosed
EP-3287122-A1 A METHOD FOR TREATING OVERACTIVE BLADDERS AND A DEVICE FOR STORAGE AND ADMINISTRATION OF TOPICAL OXYBUTYNIN COMPOSITIONS Allergan Sales, LLC (US) 2018-02-28 EP disclosed
EP-2427172-B1 A METHOD FOR TREATING OVERACTIVE BLADDERS AND A DEVICE FOR STORAGE AND ADMINISTRATION OF TOPICAL OXYBUTYNIN COMPOSITIONS ALLERGAN SALES LLC (US) 2017-11-01 EP disclosed
US-6777576-B2 NOVEL 2-(2'-CYCLOHEXEN-1'-YL)-2-HYDROXY- 2-PHENYLACETIC ACID ESTER OBTAINED BY REACTING CYCLOHEXENE AND BENZOYLFORMIC ACID ESTER IN PRESENCE OF A LEWIS ACID IS HYDROLYZED AND REDUCED TO GIVE 2-CYCLOHEXYL-2-HYDROXY-2-PHENYLACETIC ACID SUMIKA FINE CHEMICALS CO., LTD. (JP) 2004-08-17 US disclosed
US-20030013911-A1 Production method of 2-cyclohexyl- 2-hydroxy-2-phenylacetic acid intermediate therefor and production method thereof SUMIKA FINE CHEMICALS CO., LTD. (JP) 2003-01-16 US disclosed
EP-1205464-A2 Production method of 2-cyclohexyl-2-hydroxy-2-phenylacetic acid intermediate therefor and production method thereof SUMIKA FINE CHEMICALS Co., Ltd. (JP) 2002-05-15 EP disclosed
US-6060485-A UROGENITAL DISORDERS SSP CO., LTD. (JP) 2000-05-09 US disclosed
EP-0913393-A2 Arylacetic amide derivative or salt thereof, and pharmaceutical comprising it SSP Co., Ltd. (JP) 1999-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030013911-A1 Production method of 2-cyclohexyl- 2-hydroxy-2-phenylacetic acid intermediate therefor and production method thereof HCAR2, HACL2, HADHB CHRM2 3181/4885CHRM1 3986/4885KCNH2 3815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.