SCHEMBL2489064

SCHEMBL2489064

CC(=Cc1cc1=O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.50
APEX1 P27695 10/20 0.42
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
NR4A2 P43354 1/20 0.34
RXRG P48443 1/20 0.34
LTB4R Q15722 1/20 0.34
LTB4R2 Q9NPC1 1/20 0.34
HTT P42858 1/20 0.33
SLC9A1 P19634 1/20 0.33
SLC9A3 P48764 1/20 0.33
RARA P10276 1/20 0.32
RARB P10826 1/20 0.32
RARG P13631 1/20 0.32
TBXAS1 P24557 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28022677 0.77 AKR1C3 (0.47) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL8746671 0.76 AKR1C3 (0.68) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL3893886 0.76 AKR1C3 (0.68) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL31666241 0.76 AKR1C3 (0.68) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL3420812 0.76 AKR1C3 (0.45) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL8746655 0.75 AKR1C3 (0.67) AKR1C3APEX1HTTSLC9A1SLC9A3
SCHEMBL8746653 0.75 AKR1C3 (0.67) AKR1C3APEX1HTTSLC9A1SLC9A3
SCHEMBL8746662 0.74 AKR1C3 (0.59) AKR1C3APEX1RXRARXRBNR4A2
SCHEMBL10884046 0.74 AKR1C3 (0.44) AKR1C3APEX1TBXAS1
SCHEMBL10884042 0.74 AKR1C3 (0.44) AKR1C3APEX1TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2267549-B1 Carrier for electrostatic development, developer for electrostatic development, developer cartridge for electrostatic development, process cartridge and image forming apparatus FUJI XEROX CO LTD (JP) 2011-10-26 EP claimed