Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.68 |
| ▸ | APEX1 | P27695 | 8/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31666241 | 1.00 | AKR1C3 (0.68) | AKR1C3APEX1HTTRXRARXRB | |
| SCHEMBL3893886 | 1.00 | AKR1C3 (0.68) | AKR1C3APEX1HTTRXRARXRB | |
| SCHEMBL7525200 | 0.92 | AKR1C3 (0.59) | AKR1C3APEX1HTTRXRARXRB | |
| SCHEMBL8416364 | 0.92 | AKR1C3 (0.59) | AKR1C3APEX1HTTRXRARXRB | |
| SCHEMBL28588058 | 0.90 | AKR1C3 (0.57) | AKR1C3APEX1HTTRXRARXRB | |
| SCHEMBL14040079 | 0.90 | AKR1C3 (0.57) | AKR1C3APEX1HTTRXRARXRB | |
| SCHEMBL7764991 | 0.89 | AKR1C3 (0.61) | AKR1C3APEX1HTTRXRARXRB | |
| SCHEMBL7764986 | 0.89 | AKR1C3 (0.61) | AKR1C3APEX1HTTRXRARXRB | |
| SCHEMBL208434 | 0.87 | AKR1C3 (0.59) | AKR1C3APEX1LMNAMAPT | |
| SCHEMBL3736899 | 0.87 | AKR1C3 (0.59) | AKR1C3APEX1HTTRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644232-B1 | Free radical cured rubber | GOODYEAR TIRE & RUBBER (US) | 1997-03-05 | — | — | EP | claimed |