Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22895743 | 0.87 | CCNK (0.51) | CYP2C9NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL26429621 | 0.84 | HDAC1 (0.50) | CYP2C9NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL3732675 | 0.83 | CYP2C9 (0.54) | CYP2C9NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL8446674 | 0.81 | NPC1 (0.47) | CYP2C9NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL4903569 | 0.81 | POLB (0.48) | CYP2C9NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL20287527 | 0.80 | CYP2C9 (0.48) | CYP2C9NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL21515677 | 0.79 | CYP2C9 (0.58) | CYP2C9NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL18031264 | 0.78 | CYP2C9 (0.47) | CYP2C9NPC1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL31490290 | 0.78 | ROCK2 (0.50) | CYP2C9NPC1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL23769113 | 0.78 | ROCK2 (0.50) | CYP2C9NPC1SMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284651-A1 | N-(2-AMINOPHENYL)BENZAMIDE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |