Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3755257 | 0.85 | TAS1R3 (0.39) | ATMSMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL13078989 | 0.85 | TAS1R3 (0.39) | ATMSMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL29940167 | 0.84 | TDP1 (0.41) | TSHRMAPK1CYP2C19ALDH1A1CA1 | |
| SCHEMBL15799384 | 0.84 | MAPT (0.39) | TSHRMAPK1HSD17B10CYP2C19ALDH1A1 | |
| SCHEMBL17259084 | 0.84 | MAPT (0.39) | TSHRMAPK1HSD17B10CYP2C19ALDH1A1 | |
| SCHEMBL15805083 | 0.84 | MAPT (0.39) | TSHRMAPK1HSD17B10CYP2C19ALDH1A1 | |
| SCHEMBL29302480 | 0.84 | TDP1 (0.41) | TSHRMAPK1CYP2C19ALDH1A1CA1 | |
| SCHEMBL15799385 | 0.84 | MAPT (0.39) | TSHRMAPK1HSD17B10CYP2C19ALDH1A1 | |
| SCHEMBL30715022 | 0.82 | TDP1 (0.40) | TSHRMAPK1ALDH1A1CA1CA2 | |
| SCHEMBL15799264 | 0.81 | MAPT (0.40) | TSHRCYP1A2CYP2C19ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284651-A1 | N-(2-AMINOPHENYL)BENZAMIDE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |