Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | EZH1 | Q92800 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16394325 | 0.90 | FPR2 (0.44) | KDM1AHDAC8HDAC6FPR3FPR2 | |
| SCHEMBL16407913 | 0.90 | FPR2 (0.44) | KDM1AHDAC8HDAC6FPR3FPR2 | |
| SCHEMBL16394326 | 0.90 | FPR2 (0.44) | KDM1AHDAC8HDAC6FPR3FPR2 | |
| SCHEMBL17002642 | 0.87 | KDM1A (0.45) | KDM1AHDAC8HDAC6EZH2MAOA | |
| SCHEMBL24890945 | 0.87 | KDM1A (0.52) | KDM1AHDAC8HDAC6EZH2MAOA | |
| SCHEMBL17002639 | 0.87 | KDM1A (0.45) | KDM1AHDAC8HDAC6EZH2MAOA | |
| SCHEMBL24890925 | 0.85 | KDM1A (0.43) | KDM1AHDAC8HDAC6EZH2MAOA | |
| SCHEMBL17003247 | 0.85 | KDM1A (0.48) | KDM1AHDAC8HDAC6EZH2MAOA | |
| SCHEMBL17003245 | 0.85 | KDM1A (0.48) | KDM1AHDAC8HDAC6EZH2MAOA | |
| SCHEMBL15789339 | 0.84 | KDM1A (0.45) | KDM1AHDAC8HDAC6EZH2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284651-A1 | N-(2-AMINOPHENYL)BENZAMIDE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |