Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26026002 | 1.00 | TDP1 (0.39) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL22821066 | 0.80 | TDP1 (0.41) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL16787367 | 0.80 | TDP1 (0.41) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL22374283 | 0.80 | TDP1 (0.41) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL22477320 | 0.80 | TDP1 (0.41) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL24890937 | 0.77 | MEN1 (0.41) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL19143260 | 0.77 | MEN1 (0.41) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL22701449 | 0.76 | TDP1 (0.38) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL26216894 | 0.76 | TDP1 (0.36) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL13015606 | 0.75 | TDP1 (0.46) | TDP1MAOAMAOBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284651-A1 | N-(2-AMINOPHENYL)BENZAMIDE COMPOUND AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2023-01-19 | — | — | WO | disclosed |