Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16787367 | 0.83 | TDP1 (0.41) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL22477320 | 0.83 | TDP1 (0.41) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL24670129 | 0.81 | TDP1 (0.31) | TDP1MAOAMAOB | |
| SCHEMBL26026002 | 0.80 | TDP1 (0.39) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL24890940 | 0.80 | TDP1 (0.39) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL21455250 | 0.79 | MAOA (0.46) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL26023253 | 0.79 | TDP1 (0.41) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL4712142 | 0.79 | TDP1 (0.47) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL13015606 | 0.78 | TDP1 (0.46) | TDP1MAOAMAOBKMT2AMEN1 | |
| SCHEMBL21455400 | 0.77 | TDP1 (0.39) | TDP1MAOAMAOBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11285103-B2 | Degradable hydrogel under physiological conditions | HAN JIE (CN) | 2022-03-29 | — | — | US | disclosed |
| US-20200268658-A1 | Degradable hydrogel under physiological conditions | HAN JIE (CN) | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268658-A1 | Degradable hydrogel under physiological conditions | PTMS, TRHDE, PHYKPL | TDP1 2438/4885MAOA 2559/4885MAOB 2461/4885 |
| US-11285103-B2 | Degradable hydrogel under physiological conditions | PTMS, TRHDE, PHYKPL | TDP1 2438/4885MAOA 2559/4885MAOB 2461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.