Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 7/20 | 0.51 |
| ▸ | PLAT | P00750 | 6/20 | 0.51 |
| ▸ | PLG | P00747 | 5/20 | 0.51 |
| ▸ | F2 | P00734 | 5/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
| ▸ | F10 | P00742 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KLK1 | P06870 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30181046 | 1.00 | PLAU (0.51) | PLAUPLATPLGF2KLKB1 | |
| SCHEMBL30182433 | 0.94 | PLAU (0.50) | PLAUPLATPLGF2KLKB1 | |
| SCHEMBL30180767 | 0.86 | PLAU (0.48) | PLAUPLATPLGF2KLKB1 | |
| SCHEMBL24892110 | 0.85 | KMT2A (0.56) | PLAUPLATPLGF2KLKB1 | |
| Hydrochloric Acid SCHEMBL10693788 | 0.83 | NAMPT (0.60) | PLAUPLATPLGF2KLKB1 | |
| SCHEMBL30181321 | 0.83 | TMPRSS2 (0.46) | PLAUPLATPLGF2F10 | |
| SCHEMBL24891689 | 0.82 | MAPT (0.39) | PLAUPLATPLGF2KLKB1 | |
| SCHEMBL24891739 | 0.81 | PLG (0.64) | PLAUPLATPLGKLKB1PRSS1 | |
| SCHEMBL30180871 | 0.81 | KMT2A (0.63) | PLAUPLATPLGF2KLKB1 | |
| SCHEMBL30182163 | 0.81 | PLG (0.64) | PLAUPLATPLGKLKB1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |