Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 11/20 | 0.64 |
| ▸ | KLK1 | P06870 | 10/20 | 0.64 |
| ▸ | KLK6 | Q92876 | 9/20 | 0.64 |
| ▸ | PLAU | P00749 | 2/20 | 0.62 |
| ▸ | KLKB1 | P03952 | 9/20 | 0.59 |
| ▸ | PLAT | P00750 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30182163 | 1.00 | PLG (0.64) | PLGKLK1KLK6PLAUKLKB1 | |
| SCHEMBL30182852 | 0.84 | PLAU (0.60) | PLGKLK1KLK6PLAUKLKB1 | |
| SCHEMBL30182365 | 0.82 | MAPKAPK2 (0.48) | PLGKLK1KLK6PLAUKLKB1 | |
| SCHEMBL24891804 | 0.82 | MAPKAPK2 (0.48) | PLGKLK1KLK6PLAUKLKB1 | |
| SCHEMBL24892329 | 0.82 | PLAU (0.69) | PLGKLK1KLK6PLAUKLKB1 | |
| SCHEMBL28288605 | 0.81 | NPC1 (0.73) | PLGKLK1KLK6PLAUKLKB1 | |
| SCHEMBL506399 | 0.81 | NPC1 (0.73) | PLGKLK1KLK6PLAUKLKB1 | |
| SCHEMBL24891723 | 0.81 | PLAU (0.51) | PLGKLK1PLAUKLKB1PLAT | |
| SCHEMBL30181046 | 0.81 | PLAU (0.51) | PLGKLK1PLAUKLKB1PLAT | |
| SCHEMBL28200509 | 0.81 | MEN1 (0.74) | PLGKLK1KLK6PLAUKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |