⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14467514 | 1.00 | — | — | |
| SCHEMBL16761603 | 1.00 | — | — | |
| SCHEMBL31255760 | 0.97 | — | — | |
| SCHEMBL12693992 | 0.91 | — | — | |
| SCHEMBL10160748 | 0.84 | — | — | |
| SCHEMBL12147012 | 0.76 | — | — | |
| SCHEMBL17070222 | 0.76 | ALDH1A1 (0.35) | — | |
| SCHEMBL17078019 | 0.72 | TRIM24 (0.32) | — | |
| SCHEMBL17187564 | 0.72 | — | — | |
| SCHEMBL559869 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496056-B1 | NOVEL COMPOUNDS AND ANTIMALARIALS | UNIV OKAYAMA (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-7407984-B2 | Tetraoxaspriro anti-malarials | OKAYAMA UNIVERSITY (JP) | 2008-08-05 | — | — | US | disclosed |
| US-20050131058-A1 | Novel compounds and antimalarials | OKAYAMA UNIVERSITY (JP) | 2005-06-16 | — | — | US | disclosed |
| EP-1496056-A1 | NOVEL COMPOUNDS AND ANTIMALARIALS | Okayama University (JP) | 2005-01-12 | — | — | EP | disclosed |
| JP-2000229965-A | PEROXIDE DERIVATIVE HAVING ANTIMALARIAL ACTIVITY | WATAYA ARISUKE | 2000-08-22 | — | — | JP | disclosed |