Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 9/20 | 0.50 |
| ▸ | MELK | Q14680 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | TMPRSS2 | O15393 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30182351 | 1.00 | L3MBTL3 (0.54) | L3MBTL3PIK3CAMTORNAMPTMELK | |
| SCHEMBL24670771 | 0.99 | L3MBTL3 (0.55) | L3MBTL3PIK3CAMTORNAMPTMELK | |
| SCHEMBL29803472 | 0.99 | L3MBTL3 (0.55) | L3MBTL3PIK3CAMTORNAMPTMELK | |
| SCHEMBL29803702 | 0.90 | NR1H2 (0.57) | L3MBTL3PIK3CAMTORMELKTMPRSS2 | |
| SCHEMBL24670768 | 0.90 | NR1H2 (0.57) | L3MBTL3PIK3CAMTORMELKTMPRSS2 | |
| SCHEMBL24671423 | 0.86 | PIK3CA (0.48) | L3MBTL3PIK3CAMTORNAMPTHDAC1 | |
| SCHEMBL29803258 | 0.86 | PIK3CA (0.48) | L3MBTL3PIK3CAMTORNAMPTHDAC1 | |
| SCHEMBL24670772 | 0.86 | HDAC1 (0.47) | L3MBTL3PIK3CAMTORNAMPTHDAC1 | |
| SCHEMBL29803486 | 0.86 | HDAC1 (0.47) | L3MBTL3PIK3CAMTORNAMPTHDAC1 | |
| SCHEMBL23253911 | 0.85 | PIK3CA (0.53) | L3MBTL3PIK3CAMTORNAMPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |