Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30182650 | 1.00 | NAMPT (0.46) | NAMPTHDAC1HDAC6NPC1RAB9A | |
| SCHEMBL30182506 | 0.91 | NAMPT (0.44) | NAMPTHDAC1HDAC6MAPTTDP1 | |
| SCHEMBL24892259 | 0.91 | NAMPT (0.44) | NAMPTHDAC1HDAC6MAPTTDP1 | |
| SCHEMBL24892040 | 0.88 | NAMPT (0.51) | NAMPTHDAC1HDAC6NPC1RAB9A | |
| SCHEMBL24891917 | 0.87 | NAMPT (0.58) | NAMPTHDAC1HDAC6NPC1RAB9A | |
| SCHEMBL30182158 | 0.87 | NAMPT (0.58) | NAMPTHDAC1HDAC6NPC1RAB9A | |
| SCHEMBL19639347 | 0.85 | NAMPT (0.52) | NAMPTHDAC1HDAC6NPC1RAB9A | |
| SCHEMBL24892260 | 0.84 | NAMPT (0.40) | NAMPTHDAC1HDAC6MAPTTDP1 | |
| SCHEMBL24892290 | 0.83 | NR1H4 (0.49) | NAMPTHDAC1HDAC6SMN1; SMN2MAPT | |
| SCHEMBL24891759 | 0.82 | NAMPT (0.53) | NAMPTHDAC1HDAC6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |