Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | FPR3 | P25089 | 1/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30182363 | 1.00 | NAMPT (0.53) | NAMPTMAPTTP53SMN1; SMN2FPR3 | |
| SCHEMBL24891917 | 0.95 | NAMPT (0.58) | NAMPTMAPTTP53SMN1; SMN2FPR3 | |
| SCHEMBL30182158 | 0.95 | NAMPT (0.58) | NAMPTMAPTTP53SMN1; SMN2FPR3 | |
| SCHEMBL24891995 | 0.91 | FPR3 (0.55) | NAMPTMAPTTP53SMN1; SMN2FPR3 | |
| SCHEMBL24670224 | 0.89 | NAMPT (0.65) | NAMPTMAPTTP53SMN1; SMN2FPR3 | |
| SCHEMBL24891860 | 0.89 | NAMPT (0.65) | NAMPTMAPTTP53SMN1; SMN2FPR3 | |
| SCHEMBL30182509 | 0.88 | NAMPT (0.56) | NAMPTMAPTTP53SMN1; SMN2HDAC1 | |
| SCHEMBL24891974 | 0.88 | NAMPT (0.56) | NAMPTMAPTTP53SMN1; SMN2HDAC1 | |
| SCHEMBL24891782 | 0.87 | NAMPT (0.55) | NAMPTMAPTSMN1; SMN2FPR3FPR2 | |
| SCHEMBL30182354 | 0.87 | NAMPT (0.55) | NAMPTMAPTSMN1; SMN2FPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |