Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23899245 | 0.94 | NAMPT (0.72) | NAMPTHDAC1MAPTTDP1HDAC6 | |
| SCHEMBL23899122 | 0.91 | NAMPT (0.66) | NAMPTHDAC1MAPTTDP1HDAC6 | |
| SCHEMBL26032300 | 0.90 | MEN1 (0.57) | NAMPTHDAC1CA1CA2NPC1 | |
| SCHEMBL1206337 | 0.89 | NAMPT (0.55) | NAMPTHDAC1CA1CA2NPC1 | |
| SCHEMBL24891652 | 0.89 | NAMPT (0.66) | NAMPTHDAC1MAPTTDP1HDAC6 | |
| SCHEMBL2213535 | 0.88 | NAMPT (0.65) | NAMPTHDAC1NPC1RAB9AMAPT | |
| SCHEMBL24891860 | 0.88 | NAMPT (0.65) | NAMPTHDAC1MAPTTDP1HDAC6 | |
| SCHEMBL24670224 | 0.88 | NAMPT (0.65) | NAMPTHDAC1MAPTTDP1HDAC6 | |
| SCHEMBL24891767 | 0.86 | NAMPT (0.58) | NAMPTHDAC1MAPTTDP1HDAC6 | |
| SCHEMBL24891782 | 0.86 | NAMPT (0.55) | NAMPTHDAC1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |