Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | KIT | P10721 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 2/20 | 0.40 |
| ▸ | QDPR | P09417 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891779 | 0.91 | HDAC1 (0.47) | NAMPTHDAC1MAPTHDAC6ALDH1A1 | |
| SCHEMBL24670226 | 0.91 | NAMPT (0.57) | NAMPTHDAC1KITSMN1; SMN2MAPT | |
| SCHEMBL24892276 | 0.91 | NAMPT (0.57) | NAMPTHDAC1KITSMN1; SMN2MAPT | |
| SCHEMBL24891842 | 0.88 | NAMPT (0.45) | NAMPTHDAC1KITSMN1; SMN2MAPT | |
| SCHEMBL24891939 | 0.85 | NAMPT (0.38) | NAMPTHDAC1MAPTHDAC6ALDH1A1 | |
| SCHEMBL24892051 | 0.84 | NAMPT (0.53) | NAMPTHDAC1KITSMN1; SMN2MAPT | |
| SCHEMBL30182051 | 0.84 | NAMPT (0.53) | NAMPTHDAC1KITSMN1; SMN2MAPT | |
| SCHEMBL30182548 | 0.84 | NAMPT (0.54) | NAMPTHDAC1KITSMN1; SMN2MAPT | |
| SCHEMBL24891686 | 0.84 | NAMPT (0.50) | NAMPTHDAC1KITSMN1; SMN2MAPT | |
| SCHEMBL24892325 | 0.84 | NAMPT (0.50) | NAMPTHDAC1KITSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |