Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.57 |
| ▸ | PLG | P00747 | 7/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.55 |
| ▸ | PLAT | P00750 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24892329 | 0.88 | PLAU (0.69) | PLAUPLGKLKB1PLATPRSS1 | |
| SCHEMBL16316028 | 0.87 | NPC1 (0.59) | MEN1KMT2ALMNAPOLBPKM | |
| SCHEMBL27682269 | 0.86 | NR1H4 (0.48) | MEN1KMT2ALMNAPOLBPKM | |
| SCHEMBL29202217 | 0.82 | POLB (0.76) | PLAUPLGKLKB1PLATPRSS1 | |
| SCHEMBL23190878 | 0.82 | POLB (0.76) | MEN1KMT2ALMNAPOLBPKM | |
| SCHEMBL9026977 | 0.82 | POLB (0.76) | MEN1KMT2ALMNAPOLBPKM | |
| SCHEMBL15650846 | 0.82 | POLB (0.76) | PLAUPLGKLKB1PLATPRSS1 | |
| SCHEMBL28217179 | 0.82 | POLB (0.76) | PLAUPLGKLKB1PLATPRSS1 | |
| SCHEMBL4173409 | 0.81 | KLKB1 (0.62) | PLAUPLGKLKB1PLATPRSS1 | |
| SCHEMBL507027 | 0.81 | KLKB1 (0.62) | PLAUPLGKLKB1PLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |