SCHEMBL9026977

SCHEMBL9026977

Nc1ccc(NC(=O)c2ccc(C=O)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.76
MEN1 O00255 2/20 0.76
KMT2A Q03164 2/20 0.76
LMNA P02545 1/20 0.76
PKM P14618 1/20 0.76
APEX1 P27695 1/20 0.76
TDP1 Q9NUW8 1/20 0.76
PTGS1 P23219 3/20 0.61
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA12 O43570 1/20 0.59
CA9 Q16790 1/20 0.59
MAPT P10636 2/20 0.58
RAB9A P51151 5/20 0.55
NPC1 O15118 4/20 0.55
TP53 P04637 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
SNCA P37840 1/20 0.54
PRMT1 Q99873 3/20 0.54
SETD7 Q8WTS6 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23190878 1.00 POLB (0.76) POLBMEN1KMT2ALMNAPKM
SCHEMBL16316028 0.91 NPC1 (0.59) POLBMEN1KMT2ALMNAPKM
SCHEMBL137276 0.87 POLB (1.00) POLBMEN1KMT2ALMNAPKM
SCHEMBL30319980 0.87 POLB (1.00) POLBMEN1KMT2ALMNAPKM
SCHEMBL9681496 0.87 POLB (1.00) POLBMEN1KMT2ALMNAPKM
SCHEMBL1353478 0.87 POLB (1.00) POLBMEN1KMT2ALMNAPKM
SCHEMBL2128727 0.87 POLB (1.00) POLBMEN1KMT2ALMNAPKM
SCHEMBL8442129 0.85 POLB (0.96) POLBMEN1KMT2ALMNAPKM
Hydrochloric Acid SCHEMBL8640632 0.85 POLB (0.96) POLBMEN1KMT2ALMNAPKM
SCHEMBL20787000 0.85 POLB (0.73) POLBMEN1KMT2ALMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676935-B2 Polyoxymethylene resin composition HYUNDAI MOTOR COMPANY (KR) 2017-06-13 US disclosed
US-9342008-B2 Fuser member compositions XEROX CORPORATION (US) 2016-05-17 US disclosed
US-20150198915-A1 FUSER MEMBER COMPOSITIONS XEROX CORPORATION (US) 2015-07-16 US disclosed
US-20150184110-A1 POLYOXYMETHYLENE RESIN COMPOSITION KOREA ENGINEERING PLASTICS CO., LTD. (KR) 2015-07-02 US disclosed
US-8921426-B2 Cationic bis-urea compounds as effective antimicrobial agents INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-12-30 US disclosed
US-8901247-B2 Responsive polymer system and nanohybrid thin films THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-12-02 US disclosed
US-20130281515-A1 CATIONIC BIS-UREA COMPOUNDS AS EFFECTIVE ANTIMICROBIAL AGENTS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-10-24 US disclosed
US-8496616-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2013-07-30 US disclosed
US-20120220932-A1 MEDICAL DEVICE EMPLOYING LIQUID CRYSTAL BLOCK COPOLYMERS AND METHOD OF MAKING THE SAME BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-08-30 US disclosed
US-8187492-B2 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2012-05-29 US disclosed
US-20080146773-A1 Nucleophilic Acyl Substitution-based Polymerization Catalyzed by Mononuclear Oxometallic Complexes NATIONAL TAIWAN NORMAL UNIVERSITY (TW) 2008-06-19 US disclosed
EP-1889876-A1 DOPE FOR MOLDING TEIJIN LIMITED (JP) 2008-02-20 EP disclosed
US-20070191813-A1 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. 2007-08-16 US disclosed
US-20070191814-A1 Medical device employing liquid crystal block copolymers and method of making the same BOSTON SCIENTIFIC SCIMED, INC. (US) 2007-08-16 US disclosed
WO-2007042658-A1 METHOD FOR THE MODIFICATION OF POLYMER SURFACES, SUCH AS THE HYDROXYLATION OF POLYMER SURFACES, AND PRODUCTS THUS OBTAINED ALCHIMER (FR) 2007-04-19 WO disclosed
US-20070021585-A1 Nucleophilic Acyl Substitution-based Polymerization Catalyzed by Oxometallic Complexes NATIONAL TAIWAN NORMAL UNIVERSITY (TW) 2007-01-25 US disclosed
US-20070013102-A1 Method for making polybenzobisoxazole containing fiber E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
US-20070015897-A1 Method for making polybenzobisoxazole containing polymer E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
US-20070015899-A1 Polybenzobisoxazole containing fiber E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed
US-20070015898-A1 Method for making polybenzobisoxazole containing polymer E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281515-A1 CATIONIC BIS-UREA COMPOUNDS AS EFFECTIVE ANTIMICROBIAL AGENTS NOS3, NOS1, NOS2 POLB 1098/4885MEN1 3679/4885KMT2A 2488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.