Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 14/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30181076 | 1.00 | TMPRSS2 (0.42) | TMPRSS2NAMPTNPC1ALDH1A1ALOX15 | |
| SCHEMBL30181321 | 0.93 | TMPRSS2 (0.46) | TMPRSS2NAMPTNPC1ALDH1A1RAB9A | |
| SCHEMBL24669387 | 0.89 | TMPRSS2 (0.45) | TMPRSS2NAMPTNPC1ALDH1A1ALOX15 | |
| SCHEMBL24891885 | 0.89 | TMPRSS2 (0.45) | TMPRSS2NAMPTNPC1ALDH1A1ALOX15 | |
| SCHEMBL30181059 | 0.85 | TMPRSS2 (0.48) | TMPRSS2NAMPTMAPT | |
| SCHEMBL24891895 | 0.84 | TMPRSS2 (0.49) | TMPRSS2NAMPT | |
| SCHEMBL29802915 | 0.84 | TMPRSS2 (0.49) | TMPRSS2NAMPTMAPT | |
| SCHEMBL30181068 | 0.84 | TMPRSS2 (0.49) | TMPRSS2NAMPT | |
| SCHEMBL24891740 | 0.84 | NPC1 (0.41) | NAMPTNPC1ALDH1A1ALOX15RAB9A | |
| SCHEMBL24891781 | 0.84 | NPC1 (0.41) | NAMPTNPC1ALDH1A1ALOX15RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |