Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 6/20 | 0.49 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 8/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24891895 | 1.00 | TMPRSS2 (0.49) | TMPRSS2BTKNAMPTNR1H4GAA | |
| SCHEMBL24669387 | 0.86 | TMPRSS2 (0.45) | TMPRSS2BTKNAMPT | |
| SCHEMBL24891885 | 0.86 | TMPRSS2 (0.45) | TMPRSS2BTKNAMPT | |
| SCHEMBL30181059 | 0.85 | TMPRSS2 (0.48) | TMPRSS2NAMPT | |
| SCHEMBL30181321 | 0.84 | TMPRSS2 (0.46) | TMPRSS2NAMPT | |
| SCHEMBL29802915 | 0.84 | TMPRSS2 (0.49) | TMPRSS2BTKNAMPT | |
| SCHEMBL24891978 | 0.84 | TMPRSS2 (0.42) | TMPRSS2NAMPT | |
| SCHEMBL30181076 | 0.84 | TMPRSS2 (0.42) | TMPRSS2NAMPT | |
| SCHEMBL24667821 | 0.83 | TMPRSS2 (0.54) | TMPRSS2NAMPT | |
| SCHEMBL24670665 | 0.81 | TMPRSS2 (0.54) | TMPRSS2NAMPTGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | claimed |
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |