Biphenyl

Biphenyl

SCHEMBL2489290

CC(C)[C@H](N)C(=O)O.CCOCC.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.50
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
GAA P10253 1/20 0.44
PKM P14618 1/20 0.44
PTGS2 P35354 2/20 0.43
SLC1A5 Q15758 1/20 0.42
SLC15A1 P46059 1/20 0.42
SLC1A3 P43003 4/20 0.41
SLC1A2 P43004 4/20 0.41
SLC1A1 P43005 4/20 0.41
MEN1 O00255 1/20 0.41
CYP2D6 P10635 1/20 0.41
KMT2A Q03164 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
SRR Q9GZT4 2/20 0.41
PSAT1 Q9Y617 2/20 0.41
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27824248 0.88 SLC7A5 (0.65) SLC7A5CYP1A2CYP2C9CYP2C19GAA
Biphenyl SCHEMBL2494151 0.88 SLC7A5 (0.65) SLC7A5CYP1A2CYP2C9CYP2C19GAA
Valine SCHEMBL3824999 0.86 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1
Valine SCHEMBL8038980 0.84 SLC7A5 (0.65) SLC7A5SLC15A1SLC1A3SLC1A2SLC1A1
Valine SCHEMBL10718697 0.82 SLC7A5 (0.62) SLC7A5SLC15A1SLC1A3SLC1A2SLC1A1
Biphenyl SCHEMBL9412794 0.80 SMN1; SMN2 (0.52) GAA
Valine SCHEMBL2587287 0.80 SLC7A5 (0.71) SLC7A5CYP1A2CYP2C9CYP2C19GAA
Valine SCHEMBL9779769 0.78 SLC1A1 (0.58) SLC7A5CYP1A2CYP2C9CYP2C19PKM
Biphenyl SCHEMBL7637267 0.76 SMN1; SMN2 (0.48) GAA
Valine SCHEMBL8946043 0.76 SLC7A5 (0.54) SLC7A5SLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481327-B2 Methods for using congeneric, chlorinated, brominated and/or iodised, fluorinated aromatic standard compounds having two benzol rings CHIRON AS (NO) 2013-07-09 US disclosed
US-20110229973-A1 CONGENERIC, CHLORINATED, BROMINATED AND/OR IODISED, FLUORINATED AROMATIC COMPOUNDS COMPRISING TWO BENZOL RINGS IN THEIR BASIC STRUCTURE, METHOD FOR THEIR PRODUCTION AND USE THEREOF CHIRON AS (NO) 2011-09-22 US disclosed
US-20070298501-A1 Congeneric, Chlorinated, Brominated And/Or Iodised, Fluorinated Aromatic Compounds Comprising Two Benzol Rings In Their Basic Structure, Method For Their Production And Use Thereof CHIRON AS (NO) 2007-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070298501-A1 Congeneric, Chlorinated, Brominated And/Or Iodised, Fluorinated Aromatic Compounds Comprising Two Benzol Rings In Their Basic Structure, Method For Their Production And Use Thereof CBR1, CYP1A1, CYP1B1 SLC7A5 2323/4885CYP1A2 69/4885CYP2C9 312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.