Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP7 | P09237 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27824248 | 1.00 | SLC7A5 (0.65) | SLC7A5PTGS2TAAR1CYP1A2GAA | |
| Valine SCHEMBL2587287 | 0.91 | SLC7A5 (0.71) | SLC7A5PTGS2TAAR1CYP1A2GAA | |
| Biphenyl SCHEMBL2489290 | 0.88 | SLC7A5 (0.50) | SLC7A5PTGS2TAAR1CYP1A2GAA | |
| Valine SCHEMBL4582565 | 0.86 | SLC7A5 (0.88) | SLC7A5CYP1A2CYP2C9CYP2C19SLC1A3 | |
| Valine SCHEMBL28052598 | 0.86 | SLC7A5 (0.88) | SLC7A5CYP1A2CYP2C9CYP2C19SLC1A3 | |
| Valine SCHEMBL11524576 | 0.85 | SLC7A5 (0.62) | SLC7A5CYP1A2GAACYP2C9PKM | |
| Valine SCHEMBL754999 | 0.85 | SLC7A5 (0.62) | SLC7A5CYP1A2CYP2C9CYP2C19SLC1A3 | |
| Valine SCHEMBL5479272 | 0.85 | SLC7A5 (0.62) | SLC7A5CYP1A2CYP2C9CYP2C19SLC1A3 | |
| Valine SCHEMBL3709487 | 0.85 | SLC7A5 (0.62) | SLC7A5CYP1A2CYP2C9CYP2C19SLC1A3 | |
| Valine SCHEMBL6639200 | 0.85 | SLC7A5 (0.62) | SLC7A5PTGS2CYP1A2CYP2C9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102329306-A | Biphenyl valine derivative and application thereof in preparation of medicine for prevention and/or treatment of hypertension | SUZHOU BORUI BIOLOG PHARMACEUTICAL TECHNOLOGY CO LTD | 2012-01-25 | — | — | CN | claimed |
| US-8481327-B2 | Methods for using congeneric, chlorinated, brominated and/or iodised, fluorinated aromatic standard compounds having two benzol rings | CHIRON AS (NO) | 2013-07-09 | — | — | US | disclosed |
| CN-102329306-A | Biphenyl valine derivative and application thereof in preparation of medicine for prevention and/or treatment of hypertension | SUZHOU BORUI BIOLOG PHARMACEUTICAL TECHNOLOGY CO LTD | 2012-01-25 | — | — | CN | disclosed |
| CN-102329306-A | Biphenyl valine derivative and application thereof in preparation of medicine for prevention and/or treatment of hypertension | SUZHOU BORUI BIOLOG PHARMACEUTICAL TECHNOLOGY CO LTD | 2012-01-25 | — | — | CN | disclosed |
| CN-102329306-A | Biphenyl valine derivative and application thereof in preparation of medicine for prevention and/or treatment of hypertension | SUZHOU BORUI BIOLOG PHARMACEUTICAL TECHNOLOGY CO LTD | 2012-01-25 | — | — | CN | disclosed |
| US-20110229973-A1 | CONGENERIC, CHLORINATED, BROMINATED AND/OR IODISED, FLUORINATED AROMATIC COMPOUNDS COMPRISING TWO BENZOL RINGS IN THEIR BASIC STRUCTURE, METHOD FOR THEIR PRODUCTION AND USE THEREOF | CHIRON AS (NO) | 2011-09-22 | — | — | US | disclosed |
| US-20070298501-A1 | Congeneric, Chlorinated, Brominated And/Or Iodised, Fluorinated Aromatic Compounds Comprising Two Benzol Rings In Their Basic Structure, Method For Their Production And Use Thereof | CHIRON AS (NO) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070298501-A1 | Congeneric, Chlorinated, Brominated And/Or Iodised, Fluorinated Aromatic Compounds Comprising Two Benzol Rings In Their Basic Structure, Method For Their Production And Use Thereof | CBR1, CYP1A1, CYP1B1 | SLC7A5 2323/4885PTGS2 4308/4885TAAR1 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.