SCHEMBL24894040

SCHEMBL24894040

c1ccc2c(c1)Nc1cccc3c1N2c1ccccc1C31c2ccccc2-c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 1/20 0.38
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
OPRK1 P41145 1/20 0.33
KMT2A Q03164 1/20 0.33
PDGFRA P16234 1/20 0.31
FER P16591 1/20 0.31
LTK P29376 1/20 0.31
CDK8 P49336 1/20 0.31
ACVR1 Q04771 1/20 0.31
LRRK2 Q5S007 1/20 0.31
DYRK1B Q9Y463 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20938469 0.86 MEN1 (0.38) SMN1; SMN2KDM4EMEN1LMNAMAPT
SCHEMBL24894036 0.84 LMNA (0.41) AKT1SMN1; SMN2GAAKDM4ELMNA
SCHEMBL17951856 0.78 GAA (0.50) AKT1SMN1; SMN2GAAKDM4EMEN1
SCHEMBL24527786 0.77 P2RX4 (0.34) SMN1; SMN2KDM4EMEN1LMNAMAPT
SCHEMBL24608664 0.77 KMT2A (0.37) GAAMEN1LMNAMAPTKMT2A
SCHEMBL23876387 0.77 GAA (0.43) AKT1SMN1; SMN2GAAKDM4EMEN1
SCHEMBL20315956 0.76 KMT2A (0.42) SMN1; SMN2KDM4EMEN1LMNAMAPT
SCHEMBL15960559 0.76 ESR1 (0.38) SMN1; SMN2KDM4EMEN1LMNAMAPT
SCHEMBL17084399 0.75 SMN1; SMN2 (0.37) SMN1; SMN2KDM4EMEN1LMNAMAPT
SCHEMBL20444324 0.75 PDE6D (0.38) SMN1; SMN2GAAKDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023284486-A1 TETRADENTATE CYCLOMETAL PLATINUM(II) AND PALLADIUM(II) COMPLEX LUMINESCENT MATERIAL CONTAINING QUINOLINE STRUCTURAL UNIT AND APPLICATION THEREOF 浙江工业大学 2023-01-19 WO disclosed