Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940079 | 0.79 | OPRL1 (0.33) | OPRL1OPRD1OPRM1 | |
| SCHEMBL26893933 | 0.79 | OPRL1 (0.33) | OPRL1OPRD1OPRM1 | |
| SCHEMBL26893877 | 0.79 | OPRL1 (0.33) | OPRL1OPRD1OPRM1 | |
| SCHEMBL24543293 | 0.79 | OPRL1 (0.33) | OPRL1OPRD1OPRM1 | |
| SCHEMBL30885335 | 0.79 | OPRL1 (0.33) | OPRL1OPRD1OPRM1 | |
| SCHEMBL31442177 | 0.79 | OPRL1 (0.33) | OPRL1OPRD1OPRM1 | |
| SCHEMBL30922808 | 0.79 | OPRL1 (0.33) | OPRL1OPRD1OPRM1 | |
| SCHEMBL29940065 | 0.79 | OPRL1 (0.33) | OPRL1OPRD1OPRM1 | |
| SCHEMBL31667789 | 0.74 | OPRL1 (0.33) | OPRL1OPRD1OPRM1 | |
| SCHEMBL34465291 | 0.74 | OPRL1 (0.33) | OPRL1OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023284730-A1 | ALKYLIDENE DERIVATIVES AS KRAS INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |