⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10338056 | 0.93 | GLS (0.34) | — | |
| SCHEMBL24780845 | 0.81 | — | — | |
| SCHEMBL13317636 | 0.81 | — | — | |
| SCHEMBL9658533 | 0.81 | GLS (0.40) | — | |
| SCHEMBL11246632 | 0.79 | — | — | |
| SCHEMBL1265631 | 0.79 | — | — | |
| SCHEMBL1626773 | 0.79 | — | — | |
| SCHEMBL26111678 | 0.77 | — | — | |
| SCHEMBL11928221 | 0.77 | — | — | |
| SCHEMBL20221423 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243177-A1 | sGC STIMULATORS | CYCLERION THERAPEUTICS, INC. | 2025-07-31 | — | — | US | disclosed |
| CN-107021951-B | sGC stimulators | 赛克里翁治疗有限公司 | 2020-10-20 | — | — | CN | disclosed |
| US-20190345130-A1 | SGC STIMULATORS | CYCLERION THERAPEUTICS, INC. | 2019-11-14 | — | — | US | disclosed |
| US-10189809-B2 | SGC stimulators | IRONWOOD PHARMACEUTICALS, INC. (US) | 2019-01-29 | — | — | US | disclosed |
| US-20170305878-A1 | sGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2017-10-26 | — | — | US | disclosed |
| CN-107021951-A | SGC stimulators | 铁木医药有限公司 | 2017-08-08 | — | — | CN | disclosed |
| EP-3173407-A1 | SGC STIMULATORS | Ironwood Pharmaceuticals, Inc. (US) | 2017-05-31 | — | — | EP | disclosed |
| EP-2588465-B1 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS INC (US) | 2017-01-25 | — | — | EP | disclosed |
| CN-103313976-B | sGC stimulators | 铁木医药有限公司 | 2016-11-23 | — | — | CN | disclosed |
| US-20140323448-A1 | sGC STIMULATORS | Ironwood Pharmaceuticals Inc. (US) | 2014-10-30 | — | — | US | disclosed |
| WO-2012003405-A1 | SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-01-05 | — | — | WO | disclosed |
| EP-2207788-A1 | STEROIDAL [3, 2-C]PYRAZOLE COMPOUNDS, WITH GLUCOCORTICOID ACTIVITY | AstraZeneca AB (SE) | 2010-07-21 | — | — | EP | disclosed |
| US-20090286835-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-11-19 | — | — | US | disclosed |
| WO-2009044200-A1 | STEROIDAL [3, 2-C] PYRAZOLE COMPOUNDS, WITH GLUCOCORTICOID ACTIVITY | ASTRAZENECA AB (SE) | 2009-04-09 | — | — | WO | disclosed |
| EP-0739882-A1 | Novel aconitine compounds and analgesic/anti-inflammatory agent containing the same | SANWA SHOYAKU KABUSHIKI KAISHA (JP) | 1996-10-30 | — | — | EP | disclosed |
| US-5514684-A | Aconitine compounds and analgesic/anti-inflammatory agent containing the same | SANWA SHOYAKU KABUSHIKI KAISHA (JP) | 1996-05-07 | — | — | US | disclosed |
| US-5496825-A | NONTOXIC ALKALOID | SANWA SHOYAKU KABUSHIKI KAISHA (JP) | 1996-03-05 | — | — | US | disclosed |
| US-5478833-A | Low toxicity alkaloid derivative | SANWA SHOYAKU KABUSHIKI KAISHA (JP) | 1995-12-26 | — | — | US | disclosed |
| US-5478834-A | Low toxicity alkaloid derivative | SANWA SHOYAKU KABUSHIKI KAISHA (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0564648-A1 | NOVEL ACONITINE COMPOUND AND ANALGESIC/ANTIINFLAMMATORY AGENT | SANWA SHOYAKU KABUSHIKI KAISHA (JP) | 1993-10-13 | — | — | EP | disclosed |