Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24107102 | 0.87 | CTPS1 (0.72) | CTPS1 | |
| SCHEMBL24895737 | 0.82 | CTPS1 (0.60) | CTPS1 | |
| SCHEMBL21373846 | 0.78 | CTPS1 (0.69) | CTPS1 | |
| SCHEMBL24369060 | 0.76 | CTPS1 (0.61) | CTPS1 | |
| SCHEMBL29489073 | 0.76 | CTPS1 (0.61) | CTPS1 | |
| SCHEMBL24895446 | 0.74 | CTPS1 (0.69) | CTPS1 | |
| SCHEMBL30518347 | 0.73 | CTPS1 (0.90) | CTPS1 | |
| SCHEMBL21384723 | 0.73 | CTPS1 (0.90) | CTPS1 | |
| SCHEMBL22758523 | 0.73 | CTPS1 (0.54) | CTPS1 | |
| SCHEMBL29365605 | 0.73 | CTPS1 (0.89) | CTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230020663-A1 | SULFONAMIDE INHIBITORS AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230020663-A1 | SULFONAMIDE INHIBITORS AS CTPS1 INHIBITORS | CTPS1, CTPS2, TYMS | CTPS1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.