Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19014652 | 0.78 | PTGS2 (0.45) | PTGS2PTGS1BCL2L1BCL2SLC6A3 | |
| SCHEMBL24896301 | 0.77 | PTGS2 (0.44) | PTGS2PTGS1BCL2L1BCL2SLC6A3 | |
| SCHEMBL25215204 | 0.75 | BCL2L1 (0.51) | PTGS2PTGS1BCL2L1BCL2SLC6A3 | |
| SCHEMBL3420856 | 0.75 | PTGS2 (0.53) | PTGS2PTGS1BCL2L1BCL2SLC6A3 | |
| SCHEMBL3420849 | 0.75 | PTGS2 (0.49) | PTGS2PTGS1BCL2L1BCL2SLC6A3 | |
| SCHEMBL25067951 | 0.74 | PTGS2 (0.42) | PTGS2PTGS1BCL2L1BCL2SLC6A3 | |
| SCHEMBL22428759 | 0.74 | PTGS2 (0.42) | PTGS2PTGS1BCL2L1BCL2SLC6A3 | |
| SCHEMBL10058349 | 0.74 | BCL2L1 (0.50) | PTGS2PTGS1BCL2L1BCL2SLC6A3 | |
| SCHEMBL1497714 | 0.73 | PTGS2 (0.44) | PTGS2PTGS1BCL2L1BCL2SLC6A3 | |
| SCHEMBL1113744 | 0.73 | BCL2L1 (0.52) | PTGS2PTGS1BCL2L1BCL2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288100-A1 | LIPOSOMAL FORMULATIONS OF BCL INHIBITORS | CELATOR PHARMACEUTICALS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |