Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 14/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | JAK1 | P23458 | 3/20 | 0.32 |
| ▸ | TYK2 | P29597 | 3/20 | 0.32 |
| ▸ | JAK3 | P52333 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24897004 | 0.85 | GRIA2 (0.36) | GRIA2P2RX7GRM1 | |
| SCHEMBL26452701 | 0.79 | JAK2 (0.34) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL24240629 | 0.77 | L3MBTL1 (0.40) | GRIA2P2RX7GRM1 | |
| SCHEMBL12871753 | 0.74 | GRIA2 (0.35) | GRIA2P2RX7GRM1 | |
| SCHEMBL13930388 | 0.71 | GRIA2 (0.45) | GRIA2P2RX7GRM1 | |
| SCHEMBL24112467 | 0.71 | GRIA2 (0.33) | GRIA2P2RX7GRM1 | |
| SCHEMBL24896999 | 0.70 | LRRK2 (0.41) | GRIA2P2RX7GRM1 | |
| SCHEMBL805427 | 0.69 | GAA (0.44) | GRIA2 | |
| SCHEMBL15723735 | 0.68 | NTRK1 (0.37) | GRIA2 | |
| SCHEMBL24897003 | 0.68 | IRAK4 (0.41) | GRIA2P2RX7GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023285497-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE AS ANTIBIOTICS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-01-19 | — | — | WO | disclosed |