SCHEMBL248974

SCHEMBL248974

Cc1[nH]c2ccccc2c1C=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.61
GFER P55789 1/20 0.61
KMT2A Q03164 9/20 0.55
MEN1 O00255 8/20 0.55
MAPT P10636 8/20 0.55
ALDH1A1 P00352 4/20 0.55
LMNA P02545 3/20 0.55
AHR P35869 2/20 0.55
RAB9A P51151 4/20 0.53
GAA P10253 3/20 0.53
NPC1 O15118 3/20 0.53
CYP1A2 P05177 3/20 0.53
NPSR1 Q6W5P4 2/20 0.53
CYP2D6 P10635 2/20 0.53
HTT P42858 2/20 0.53
ALPG P10696 1/20 0.53
CYP2C19 P33261 2/20 0.50
TNKS2 Q9H2K2 1/20 0.50
PSMD14 O00487 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29378092 1.00 HPGD (0.61) HPGDGFERKMT2AMEN1MAPT
Acetic Acid SCHEMBL28679441 0.91 MAPT (0.60) HPGDGFERKMT2AMEN1MAPT
SCHEMBL19846952 0.87 HTT (0.56) HPGDGFERKMT2AMEN1MAPT
SCHEMBL15161664 0.85 HPGD (0.50) HPGDGFERKMT2AMEN1MAPT
SCHEMBL30760676 0.85 HPGD (0.57) HPGDGFERKMT2AMEN1MAPT
SCHEMBL31264349 0.82 KMT2A (0.57) HPGDGFERKMT2AMEN1MAPT
SCHEMBL27638400 0.81 ALDH1A1 (0.66) HPGDGFERKMT2AMEN1MAPT
SCHEMBL14519076 0.81 GSK3B (0.53) HPGDKMT2AMEN1MAPTALDH1A1
SCHEMBL6545653 0.80 HPGD (0.61) HPGDGFERKMT2AMEN1MAPT
SCHEMBL7599597 0.80 HPGD (0.61) HPGDGFERKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 785 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119874681-A Indole derivative, preparation method thereof and application of indole derivative in resisting liver cancer 中国人民解放军北部战区总医院 2025-04-25 CN claimed
CN-114437092-B Chiral tetrahydrocarbazole polycyclic derivative and preparation method and application thereof 贵州中医药大学 2024-02-06 CN claimed
CN-112679540-B Chiral sulfinamide phosphine compound Na-Phos based on indole ring skeleton and preparation method thereof 华东师范大学 2023-04-21 CN claimed
CN-114437092-A Chiral tetrahydrocarbazole polycyclic derivative and preparation method and application thereof 贵州中医药大学 2022-05-06 CN claimed
CN-112679540-A Chiral sulfinamide phosphine compound Na-Phos based on indole ring skeleton and preparation method thereof 华东师范大学 2021-04-20 CN claimed
CN-111039929-A Antitumor compound NY and series derivatives thereof 中国人民解放军北部战区总医院 2020-04-21 CN claimed
CN-107043344-B Preparation, structure and the purposes of 4-acetylbiphenyl hydrazone-N- methyl -3- indolecarboxaldehyde Schiff base 齐鲁工业大学 2019-07-05 CN claimed
CN-107043344-A Preparation, structure and the purposes of the indolecarboxaldehyde Schiff base of 4-acetylbiphenyl hydrazone N methyl 3 齐鲁工业大学 2017-08-15 CN claimed
EP-2358343-B1 METHOD FOR DECOLOURING KERATINOUS FIBRES HENKEL AG & CO KGAA (DE) 2016-10-19 EP claimed
WO-2012145069-A2 MATERIALS AND METHODS USEFUL TO INDUCE CELL DEATH VIA METHUOSIS THE UNIVERSITY OF TOLEDO (US) 2012-10-26 WO claimed
WO-2003030842-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
WO-2003030847-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-1300132-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-1300133-A2 Agent for dyeing keratinous fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2003-04-09 EP claimed
EP-0690054-B1 1-Amino-2-cyclohexene derivatives and production process therefor KURARAY CO (JP) 2002-11-20 EP claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
EP-0873744-A2 Use of heterocyclic carbonyl compounds for dying keratinous fibers Henkel Kommanditgesellschaft auf Aktien (DE) 1998-10-28 EP claimed
US-5587486-A CONDENSATION; CARBONYLATION; HYDROLYSIS; INTERMEDIATES IN THE PRODUCTION OF MEDICINAL AND AGRICULTURAL AGENTS KURARAY CO., LTD. (JP) 1996-12-24 US claimed
EP-0690054-A1 1-Amino-2-cyclohexene derivatives and production process therefor KURARAY CO., LTD. (JP) 1996-01-03 EP claimed