Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FCER2 | P06734 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26774841 | 0.89 | MME (0.36) | MMEALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL26858396 | 0.89 | ALDH1A1 (0.33) | MMEALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL24915216 | 0.88 | MME (0.34) | MMEALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL26858193 | 0.85 | MME (0.31) | MMEALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL26857875 | 0.82 | MME (0.33) | MME | |
| SCHEMBL26857865 | 0.78 | MME (0.34) | MMEALDH1A1LMNAMAPTPTGS2 | |
| SCHEMBL20910230 | 0.77 | FCER2 (0.35) | ALDH1A1FCER2ACE | |
| SCHEMBL26169813 | 0.74 | FCER2 (0.36) | FCER2ACE | |
| SCHEMBL26518372 | 0.73 | FCER2 (0.33) | TDP1FCER2 | |
| SCHEMBL13948303 | 0.72 | CES1 (0.37) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288213-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-01-19 | — | — | WO | disclosed |